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This post will help you to setup a WordPress Multisite with subdomains so we can manage multiple sites under different subdomains. e.g. support.mysite.com blog.mysite.com
This post will guide you on how to set up a WordPress Multisite with subdirectories so you can manage multiple sites under different paths. e.g. site.com/support/ and site.com/eu/ etc.
This Post is a compendium of Conditionals and a list of Good and Bad Parts, to definitively help you to decide when to use WordPress Multisite. If Multisite is for you